Acidic fibroblast growth factor attenuates type 2 diabetes-induced demyelination via suppressing oxidative stress damage

Abstract Prolonged type 2 diabetes mellitus (T2DM) produces a common complication, peripheral neuropathy, which is accompanied by nerve fiber disorder, axon atrophy, and demyelination. Growing evidence has characterized the beneficial effects of acidic fibroblast growth factor (aFGF) and shown that...

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Bibliographic Details
Main Authors: Rui Li, Beini Wang, Chengbiao Wu, Duohui Li, Yanqing Wu, Libing Ye, Luxia Ye, Xiongjian Chen, Peifeng Li, Yuan Yuan, Hongyu Zhang, Ling Xie, Xiaokun Li, Jian Xiao, Jian Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03407-2