The screening for marine fungal strains with high potential in alkaloids production by in situ colony assay and LC-MS/MS based secondary metabolic profiling

The screening for marine fungal strains with high potential in alkaloids production by in situ colony assay and LC-MS/MS based secondary metabolic profiling

BackgroundAlkaloids are the second primary class of secondary metabolites (SMs) from marine organisms, most of which have antioxidant, antitumor, antibacterial, anti-inflammatory, and other activities. However, the SMs obtained by traditional isolation strategies have drawbacks such as highly redupl...

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Bibliographic Details
Main Authors: Tiantian Lu, Yayue Liu, Longjian Zhou, Qingnan Liao, Yingying Nie, Xingyuan Wang, Xiaoling Lei, Pengzhi Hong, Yan Feng, Xueqiong Hu, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Microbiology
Subjects:
alkaloids
in situ colony screening
LC-MS/MS
Penicillium mallochii
azaphilone
anti-neuroinflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1144328/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1144328/full

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