Characterization of multiple soluble immune checkpoints in individuals with different Mycobacterium tuberculosis infection status and dynamic changes during anti-tuberculosis treatment

Abstract Background Immune checkpoints are crucial for the maintenance of subtle balance between self-tolerance and effector immune responses, but the role of soluble immune checkpoints (sICs) in Mycobacterium tuberculosis (M. tb) infection remains unknown. We assessed the levels of multiple sICs in...

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Bibliographic Details
Main Authors: Huaxin Chen, Jingyu Zhou, Xinguo Zhao, Qianqian Liu, Lingyun Shao, Yehan Zhu, Qinfang Ou
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Infectious Diseases
Subjects:
Online Access:https://doi.org/10.1186/s12879-022-07506-z