UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

Abstract Lymphatic metastasis is the most common pattern of bladder cancer (BCa) metastasis and has an extremely poor prognosis. Emerging evidence shows that ubiquitination plays crucial roles in various processes of tumors, including tumorigenesis and progression. However, the molecular mechanisms...

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Bibliographic Details
Main Authors: Kanghua Xiao, Shengmeng Peng, Junlin Lu, Ting Zhou, Xuwei Hong, Siting Chen, Guangyao Liu, Hong Li, Jian Huang, Xu Chen, Tianxin Lin
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05938-2

Internet

https://doi.org/10.1038/s41419-023-05938-2

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