Golgi Phosphoprotein 3 Promotes Colon Cancer Cell Metastasis Through STAT3 and Integrin α3 Pathways

Golgi Phosphoprotein 3 Promotes Colon Cancer Cell Metastasis Through STAT3 and Integrin α3 Pathways

Background: Golgi phosphoprotein 3 (GOLPH3) overexpression was recently reported to be associated with a poor clinical outcome in patients with colorectal cancer (CRC). However, the underlying molecular mechanism through which GOLPH3 promotes CRC metastasis remains poorly understood.Methods:In vitro...

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Bibliographic Details
Main Authors: Anpei Huang, Ruizhi Wang, Ji Cui, Ying Gao, Zheng Yin, Lianzhou Chen, Meifang He, Wen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
GOLPH3
stat3
integrin α3
cell invasion and migration
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.808152/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.808152/full

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