A comparative magnetic resonance spectroscopy study of GABA+ and glutamate referenced to creatine and phosphocreatine in the left dorsolateral prefrontal cortex of perimenopausal women and women of reproductive age

A comparative magnetic resonance spectroscopy study of GABA+ and glutamate referenced to creatine and phosphocreatine in the left dorsolateral prefrontal cortex of perimenopausal women and women of reproductive age

ObjectiveThe perimenopause is associated with an increased risk of developing a major depressive (MD) episode. The biological changes occurring during perimenopause responsible for this increased risk of depression remain to be elucidated. Postmortem and magnetic resonance spectroscopy (MRS) studies...

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Bibliographic Details
Main Authors: Kim H. Tran, Jessica Luki, Sarah Hanstock, Christopher C. Hanstock, Peter Seres, Katherine Aitchison, Tami Shandro, Jean-Michel Le Melledo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Psychiatry
Subjects:
perimenopause
magnetic resonance spectroscopy (MRS)
glutamate
GABA
left dorsolateral prefrontal cortex (DLPFC)
depression
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.989050/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.989050/full

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