Group I mGluRs in Therapy and Diagnosis of Parkinson’s Disease: Focus on mGluR5 Subtype

Group I mGluRs in Therapy and Diagnosis of Parkinson’s Disease: Focus on mGluR5 Subtype

Metabotropic glutamate receptors (mGluRs; members of class C G-protein-coupled receptors) have been shown to modulate excitatory neurotransmission, regulate presynaptic extracellular glutamate levels, and modulate postsynaptic ion channels on dendritic spines. mGluRs were found to activate myriad si...

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Bibliographic Details
Main Authors: Shofiul Azam, Md. Jakaria, JoonSoo Kim, Jaeyong Ahn, In-Su Kim, Dong-Kug Choi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
glutamate signalling
metabotropic glutamate receptors
C G-protein-coupled receptors
neurodegenerative diseases
positron emission tomography
radioligands
Online Access:https://www.mdpi.com/2227-9059/10/4/864

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https://www.mdpi.com/2227-9059/10/4/864

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