Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial.

A randomized multicenter phase II trial was conducted to assess the sequential treatment strategy using FOLFIRI.3 and gemcitabine alternately (Arm 2) compared to gemcitabine alone (Arm 1) in patients with metastatic non pre-treated pancreatic adenocarcinoma. The primary endpoint was the progression-...

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Main Authors: Amélie Anota, Guillaume Mouillet, Isabelle Trouilloud, Anne-Claire Dupont-Gossart, Pascal Artru, Thierry Lecomte, Aziz Zaanan, Mélanie Gauthier, Francine Fein, Olivier Dubreuil, Sophie Paget-Bailly, Julien Taieb, Franck Bonnetain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4444351?pdf=render