Antitumor and off-target effects of cholesterol-conjugated let-7a mimics in an orthotopic hepatocellular carcinoma xenograft nude mouse model
Objective:. To explore the antitumor and potential off-target effects of systemically delivered cholesterol-conjugated let-7a mimics (Chol-let-7a) and control mimics (Chol-miRCtrl) on hepatocellular carcinoma in vivo. Methods:. The antitumor effects of two intravenous dosing regimens of Chol-let-7a...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health
2022-12-01
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| Series: | Journal of Bio-X Research |
| Online Access: | http://journals.lww.com/10.1097/JBR.0000000000000103 |