Drosophila melanogaster: A new model to study cisplatin-induced neurotoxicity
Platinum-based compounds are widely used and effective chemotherapeutic agents; however, sensory peripheral neuropathy is a dose-limiting and long term side effect for 20–30% of patients. A critical question is whether the mechanisms of cell death underlying clinical efficacy can be separated from t...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-08-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111001173 |