Mitochondrial C4375T mutation might be a molecular risk factor in a maternal Chinese hypertensive family under haplotype C

Mitochondrial C4375T mutation might be a molecular risk factor in a maternal Chinese hypertensive family under haplotype C

Here, we reported a Han Chinese essential hypertensive pedigree based on clinical hereditary and molecular data. To know the molecular basis on this family, mitochondrial genome of one proband from the family was identified through direct sequencing analysis. The age of onset year and affected degre...

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Bibliographic Details
Main Authors: Hong Chen, Min Sun, Zhen Fan, Maoqing Tong, Guodong Chen, Danhui Li, Jihui Ye, Yumin Yang, Yongding Zhu, Jianhua Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-08-01
Series:Clinical and Experimental Hypertension
Subjects:
hypertension
matrilineal
mitochondrial dna
gene mutation
halopgroup
Online Access:http://dx.doi.org/10.1080/10641963.2017.1403622

Internet

http://dx.doi.org/10.1080/10641963.2017.1403622

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