Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition: The Big Step Forward in Lipid Control

The breakthrough discovery of proprotein convertase subtilisin/kexin type 9 (PCSK9) 20 years ago revolutionised the current understanding of cholesterol homeostasis. Genetic studies have shown that gain-of-function mutations in PCSK9 lead to elevated LDL cholesterol and increased risk of atheroscler...

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Bibliographic Details
Main Authors: Rishi Rikhi, Michael D Shapiro
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-06-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2023.14