Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition: The Big Step Forward in Lipid Control
The breakthrough discovery of proprotein convertase subtilisin/kexin type 9 (PCSK9) 20 years ago revolutionised the current understanding of cholesterol homeostasis. Genetic studies have shown that gain-of-function mutations in PCSK9 lead to elevated LDL cholesterol and increased risk of atheroscler...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Radcliffe Medical Media
2023-06-01
|
Series: | European Cardiology Review |
Online Access: | https://www.ecrjournal.com/articleindex/ecr.2023.14 |