Muscle metabolic stress determines cancer cachexia severity in mice

Muscle metabolic stress determines cancer cachexia severity in mice

Objectives: To determine the metabolic effects of cancer-conditioned media on myotube metabolism and to understand whether the variability of these effects is associated with cancer cachexia progression.Materials and methods: We established single-cell clones from murine Lewis lung carcinoma (LLC) c...

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Bibliographic Details
Main Authors: Christiano Alves, Laurie Goodyear, Patricia Brum
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
muscle wasting
atrophy
oxidative metabolism
oxidative stress
lung carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1033932/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.1033932/full

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