Prognostic significance of fludeoxyglucose positron emission tomography delta radiomics following bridging therapy in patients with large B-cell lymphoma undergoing CAR T-cell therapy

Prognostic significance of fludeoxyglucose positron emission tomography delta radiomics following bridging therapy in patients with large B-cell lymphoma undergoing CAR T-cell therapy

Purpose/objective(s)Bridging radiation therapy (bRT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell therapy for large B-cell lymphoma (LBCL). It is unknown how the extent of cytoreduction during bRT impacts outcomes.Materials/methodsWe retrospectively reviewed patient...

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Bibliographic Details
Main Authors: Colton Ladbury, Claire Hao, William Tyler Watkins, Sagus Sampath, Jeffrey Wong, Arya Amini, Karen Sokolov, Jekwon Yeh, Karine A. Al Feghali, Dorine de Jong, Arjun Maniyedath, Shervin Shirvani, Liana Nikolaenko, Matthew Mei, Alex Herrera, Leslie Popplewell, Lihua Elizabeth Budde, Savita Dandapani
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
large B-cell lymphoma (LBCL)
delta radiomics
bridging radiation
chimeric antigen receptor T-cell (CAR T)
positron emission tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1419788/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1419788/full

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