Pre-targeting and direct immunotargeting of liposomal drug carriers to ovarian carcinoma.

Pre-targeting and direct immunotargeting of liposomal drug carriers to ovarian carcinoma.

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-normal tissue concentrations should be increased t...

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Bibliographic Details
Main Authors: Julia Lehtinen, Mari Raki, Kim A Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3406029?pdf=render

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http://europepmc.org/articles/PMC3406029?pdf=render

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