α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) in Rat Mesangial Cells

α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) in Rat Mesangial Cells

Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) is a key mediator of inflammation, and consequently huge efforts have been devoted to the development of novel agents able to regulate its formation. In this work, we present the synthesis of various α-ketoheterocycles and a study...

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Bibliographic Details
Main Authors: Anastasia Psarra, Maria A. Theodoropoulou, Martin Erhardt, Marina Mertiri, Christiana Mantzourani, Sofia Vasilakaki, Victoria Magrioti, Andrea Huwiler, George Kokotos
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
anti-inflammatory
inhibition
α-ketobenzothiazoles
mesangial cells
prostaglandin E<sub>2</sub>
Online Access:https://www.mdpi.com/2218-273X/11/2/275

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https://www.mdpi.com/2218-273X/11/2/275

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