Claudin-18.2 mediated interaction of gastric Cancer cells and Cancer-associated fibroblasts drives tumor progression

Claudin-18.2 mediated interaction of gastric Cancer cells and Cancer-associated fibroblasts drives tumor progression

Abstract Background Claudin-18.2 (CLDN18.2) has emerged as an alluring therapeutic target against gastrointestinal tumors in recent years. However, a thorough understanding of its regulatory mechanism in gastric cancer remains elusive. Methods We presented a comprehensive study comprising 185 gastri...

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Bibliographic Details
Main Authors: Shengde Liu, Zizhen Zhang, Lei Jiang, Miao Zhang, Cheng Zhang, Lin Shen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Gastric cancer
CLDN18.2
cancer-associated fibroblasts
Metastasis
Adhesion
S100A4
Online Access:https://doi.org/10.1186/s12964-023-01406-8

Internet

https://doi.org/10.1186/s12964-023-01406-8

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