Identification of Naturally Processed Epitope Region Using Artificial APC Expressing a Single HLA Class I Allotype and mRNA of HCMV pp65 Antigen Fragments

Identification of Naturally Processed Epitope Region Using Artificial APC Expressing a Single HLA Class I Allotype and mRNA of HCMV pp65 Antigen Fragments

Recently, long synthetic peptides or in silico-predicted epitope peptides have been used to identify T cell epitopes, but these approaches may not be suitable for investigating naturally processed epitopes. Here, mRNAs, including fragments or predicted epitope sequences of HCMV pp65 antigen, were ge...

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Bibliographic Details
Main Authors: Hong-Seon Pyo, Cheol-Hwa Hong, Haeyoun Choi, In-Cheol Baek, Tai-Gyu Kim
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Vaccines
Subjects:
epitope identification method
HLA class I
artificial antigen-presenting cell
T cell epitope
transcriptionally active PCR
mRNA
Online Access:https://www.mdpi.com/2076-393X/10/5/787

Internet

https://www.mdpi.com/2076-393X/10/5/787

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