AlphaFold prediction of structural ensembles of disordered proteins

Abstract Deep learning methods of predicting protein structures have reached an accuracy comparable to that of high-resolution experimental methods. It is thus possible to generate accurate models of the native states of hundreds of millions of proteins. An open question, however, concerns whether t...

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Bibliographic Details
Main Authors: Z. Faidon Brotzakis, Shengyu Zhang, Mhd Hussein Murtada, Michele Vendruscolo
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56572-9