Heterologous Expression and Assembly of Human TLR Signaling Components in <i>Saccharomyces cerevisiae</i>

Heterologous Expression and Assembly of Human TLR Signaling Components in <i>Saccharomyces cerevisiae</i>

Toll-like receptor (TLR) signaling is key to detect pathogens and initiating inflammation. Ligand recognition triggers the assembly of supramolecular organizing centers (SMOCs) consisting of large complexes composed of multiple subunits. Building such signaling hubs relies on Toll Interleukin-1 Rece...

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Bibliographic Details
Main Authors: Julia María Coronas-Serna, Elba del Val, Jonathan C. Kagan, María Molina, Víctor J. Cid
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomolecules
Subjects:
<i>Saccharomyces cerevisiae</i>
humanized yeast
innate immunity
ERMES
MyD88
TIRAP
Online Access:https://www.mdpi.com/2218-273X/11/11/1737

Internet

https://www.mdpi.com/2218-273X/11/11/1737

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