Validation of Immunohistochemistry for the Detection of <i>BRAF</i> V600E-Mutated Lung Adenocarcinomas

<i>BRAF</i> V600E mutation, a missense mutation in exon 15 resulting in valine substitution for glutamate at position 600 within the kinase domain of BRAF oncogene, is found in a subset of lung adenocarcinoma (ADC). The usefulness of immunohistochemistry (IHC) as an alternative diagnosti...

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Bibliographic Details
Main Authors: Chien-Hung Gow, Min-Shu Hsieh, Yen-Ting Lin, Yi-Nan Liu, Jin-Yuan Shih
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/6/866