Efavirenz dissolution enhancement V - A combined top down/bottom up approach on nanocrystals formulation

Abstract Efavirenz is one of the most commonly used drugs in HIV therapy. However the low water solubility tends to result in low bioavailability. Drug nanocrystals, should enhance the dissolution and consequently bioavailability. The aim of the present study was to obtain EFV nanocrystals prepared...

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Bibliographic Details
Main Authors: Gabriela Julianelly Sartori, Livia Deris Prado, Helvécio Vinícius Antunes Rocha
Format: Article
Language:English
Published: Universidade de São Paulo 2022-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100529&tlng=en