The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

Abstract CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1 as a regulator of malignant chordoma...

Full description

Bibliographic Details
Main Authors: Jingbing Lou, Hongliang Zhang, Qingshan Huang, Chenglong Chen, Wei Wang, Jianfang Niu, Jiuhui Xu, Tingting Ren, Yi Huang, Xiaodong Tang, Wei Guo
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01332-1

Internet

https://doi.org/10.1038/s41420-023-01332-1

Similar Items