MHESMMR: a multilevel model for predicting the regulation of miRNAs expression by small molecules

MHESMMR: a multilevel model for predicting the regulation of miRNAs expression by small molecules

Abstract According to the expression of miRNA in pathological processes, miRNAs can be divided into oncogenes or tumor suppressors. Prediction of the regulation relations between miRNAs and small molecules (SMs) becomes a vital goal for miRNA-target therapy. But traditional biological approaches are...

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Bibliographic Details
Main Authors: Yong-Jian Guan, Chang-Qing Yu, Li-Ping Li, Zhu-Hong You, Meng-meng Wei, Xin-Fei Wang, Chen Yang, Lu-Xiang Guo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Bioinformatics
Subjects:
LINE
microRNA
Small molecule
Generally attributed multiplex heterogeneous network embedding
Machine learning
Online Access:https://doi.org/10.1186/s12859-023-05629-x

Internet

https://doi.org/10.1186/s12859-023-05629-x

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