Prevalence of SARS-CoV-2 Omicron Sublineages and Spike Protein Mutations Conferring Resistance against Monoclonal Antibodies in a Swedish Cohort during 2022–2023

Prevalence of SARS-CoV-2 Omicron Sublineages and Spike Protein Mutations Conferring Resistance against Monoclonal Antibodies in a Swedish Cohort during 2022–2023

Monoclonal antibodies (mAbs) are an important treatment option for COVID-19 caused by SARS-CoV-2, especially in immunosuppressed patients. However, this treatment option can become ineffective due to mutations in the SARS-CoV-2 genome, mainly in the receptor binding domain (RBD) of the spike (S) pro...

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Bibliographic Details
Main Authors: Jonathan Haars, Navaneethan Palanisamy, Frans Wallin, Paula Mölling, Johan Lindh, Martin Sundqvist, Patrik Ellström, René Kaden, Johan Lennerstrand
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Microorganisms
Subjects:
SARS-CoV-2
coronavirus
monoclonal antibodies
resistance
nanopore
Sweden
Online Access:https://www.mdpi.com/2076-2607/11/10/2417

Internet

https://www.mdpi.com/2076-2607/11/10/2417

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