Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation

The nucleotide-binding domain leucine-rich repeat-receptor, pyrin domain-containing-3 (NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1, which in turn participates in the maturation of interleukin (IL)-1β and IL-18, which are mainly secreted via pyroptosis. Pyropt...

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Bibliographic Details
Main Authors: Fernando Lucas-Ruiz, Alejandro Peñín-Franch, José Antonio Pons, Pablo Ramírez, Pablo Pelegrín, Santiago Cuevas, Alberto Baroja-Mazo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/14396