Pathophysiology of diabetes mellitus type 2: beyond the duo "insulin resistance-secretion deficit"

T2DM involves at least two primary pathogenic mechanisms: (a) a progressive decline in pancreatic islet cell function resulting in reduced insulin secretion and (b) peripheral insulin resistance resulting in a decrease in the metabolic responses to insulin. This dynamic interaction between insulin s...

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Bibliographic Details
Main Authors: C. A. Carrera Boada, J. M. Martínez-Moreno
Format: Article
Language:English
Published: Arán Ediciones, S. L. 2013-01-01
Series:Nutrición Hospitalaria
Subjects:
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000800012&lng=en&tlng=en