Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet

DNA damage is an essential component of the genesis of colonic cancer. Gut microbial products and food components are thought to be principally responsible for the damage that initiates disease progression. Modified Ames tests and Comet assays have been developed for measuring mutagenicity and geno...

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Bibliographic Details
Main Authors: Silvia eGratz, R. John eWallace, Hani eEl-Nezami
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00004/full