Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

Metastatic melanoma is a significant clinical problem with a 5-year survival rate of only 15–20%. Recent approval of new immunotherapies and targeted inhibitors have provided much needed options for these patients, in some cases promoting dramatic disease regressions. In particular, antibody-based t...

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Bibliographic Details
Main Authors: Kathleen M. Kokolus, Jeremy S. Haley, Emily J. Koubek, Raghavendra Gowda, Saketh S. Dinavahi, Arati Sharma, David F. Claxton, Klaus F. Helm, Joseph J. Drabick, Gavin P. Robertson, Jeffrey D. Neighbors, Raymond J. Hohl, Todd D. Schell
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
schweinfurthin
pd-1
melanoma
mice
immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1539614

Internet

http://dx.doi.org/10.1080/2162402X.2018.1539614

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