Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis

Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis

The existence of a hyperinflammatory state has been observed in patients with invasive fungal infections (IFI). It is being postulated whether morbidity from IFI may, in part, be a consequence of an unnecessarily prolonged or exaggerated proinflammatory immune response including interleukin 6 (IL-6)...

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Bibliographic Details
Main Authors: Zhaohong Tan, Michelle Meng Huang Mok, Win Mar Soe, Thomas Paulraj Thamboo, Jessamine Geraldine Goh, Qi Hui Sam, Motomi Osato, Sharada Ravikumar, Louis Yi Ann Chai
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Fungi
Subjects:
<i>Candida albicans</i>
interleukin 6 blockade
inflammation
immunomodulation
monoclonal antibody
Online Access:https://www.mdpi.com/2309-608X/7/8/656

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https://www.mdpi.com/2309-608X/7/8/656

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