Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters

Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters

Abstract With recent advances in immune checkpoint inhibitors (ICIs), immunotherapy has become the standard treatment for various malignant tumors. Their indications and dosages have been determined empirically, taking individually conducted clinical trials into consideration, but without a standard...

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Bibliographic Details
Main Authors: Wataru Nishi, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Kensho Saito, Yosuke Yoshida, Tetsushi Nishikawa, Tomohiro Takehara, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, Tadashi Yokosuka
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38512-7

Internet

https://doi.org/10.1038/s41467-023-38512-7

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