Expression of the C-allele of intronic rs8192675 in SLC2A2 is associated with improved glucose response to metformin

Abstract Glucose is a critical nutrient for energy metabolism. The SLC2A2 gene is essential for glucose sensing and homeostasis, as it encodes the facilitated glucose transporter GLUT2. During diabetes treatment, the C-allele of rs8192675 in SLC2A2 has been found to regulate the action of metformin...

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Bibliographic Details
Main Authors: Wanjun Wang, Suying Chen, Yilei Jiang, Jianhong Ji, Ruochen Cong
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2024-09-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572024000400701&lng=en&tlng=en