The skin as a metabolic and immune-competent organ: Implications for drug-induced skin rash

Current advances in the study of cutaneous adverse drug reactions can be attributed to the recent understanding that the skin is both a metabolically and immunologically competent organ. The ability of the skin to serve as a protective barrier with limited drug biotransformation ability, yet highly...

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Bibliographic Details
Main Authors: Amy Sharma, Yoshiro Saito, Shuen-Iu Hung, Dean Naisbitt, Jack Uetrecht, Jeanine Bussiere
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Immunotoxicology
Subjects:
Online Access:http://dx.doi.org/10.1080/1547691X.2018.1514444