Administration of Slow-Release Synthetic Prostacyclin Agonist Promoted Angiogenesis and Skeletal Muscle Regeneration for Limb Ischemia

Administration of Slow-Release Synthetic Prostacyclin Agonist Promoted Angiogenesis and Skeletal Muscle Regeneration for Limb Ischemia

Gene or cell therapy is currently not fully efficacious for arteriosclerosis obliterans (ASO). In this study, we determined whether YS-1402, a slow-release synthetic prostacyclin agonist, promoted neovascularization and skeletal muscle regeneration in a mouse model of critical limb ischemia (CLI). W...

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Bibliographic Details
Main Authors: Takaya Nakagawa, Shigeru Miyagawa, Takashi Shibuya, Yoshiki Sakai, Akima Harada, Kenichi Watanabe, Yoshiki Sawa
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
critical limb ischemia
YS-1402
angiogenesis
skeletal muscle regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301091

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http://www.sciencedirect.com/science/article/pii/S2329050120301091

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