Granulocytic Myeloid-Derived Suppressor Cells as Negative Regulators of Anticancer Immunity

The immune system plays a critical role in cancer progression and response to therapy. However, the immune system can be compromised during the neoplastic process. Notably, the myeloid lineage, which gives rise to granulocytic cells, including neutrophils, is a well-recognized target of tumor-mediat...

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Bibliographic Details
Main Authors: Elliot D. Kramer, Scott I. Abrams
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01963/full