Photodynamic Therapy Activity of New Porphyrin-Xylan-Coated Silica Nanoparticles in Human Colorectal Cancer

Photodynamic Therapy Activity of New Porphyrin-Xylan-Coated Silica Nanoparticles in Human Colorectal Cancer

Photodynamic therapy (PDT) using porphyrins has been approved for treatment of several solid tumors due to the generation of cytotoxic reactive oxygen species (ROS). However, low physiological solubility and lack of selectivity towards tumor sites are the main limitations of their clinical use. Nano...

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Bibliographic Details
Main Authors: Ludovic Bretin, Aline Pinon, Soukaina Bouramtane, Catherine Ouk, Laurence Richard, Marie-Laure Perrin, Alain Chaunavel, Claire Carrion, Frédérique Bregier, Vincent Sol, Vincent Chaleix, David Yannick Leger, Bertrand Liagre
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
anticancer drug
porphyrin
silica nanoparticles
drug delivery
photodynamic therapy
Online Access:https://www.mdpi.com/2072-6694/11/10/1474

Internet

https://www.mdpi.com/2072-6694/11/10/1474

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