HLA-B*46:01:01:01 and HLA-DRB1*09:01:02:01 are associated with anti-rHuEPO-induced pure red cell aplasia

HLA-B*46:01:01:01 and HLA-DRB1*09:01:02:01 are associated with anti-rHuEPO-induced pure red cell aplasia

Abstract Treatment of anemia in patients with chronic kidney disease (CKD) with recombinant human erythropoietin (rHuEPO) can be disrupted by a severe complication, anti-rHuEPO-induced pure red cell aplasia (PRCA). Specific HLA genotypes may have played a role in the high incidence of PRCA in Thai p...

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Bibliographic Details
Main Authors: Thitima Benjachat Suttichet, Monpat Chamnanphon, Monnat Pongpanich, Sarun Chokyakorn, Pawinee Kupatawintu, Chalurmpon Srichomthong, Wanna Chetruengchai, Hathaichanok Chuntakaruk, Thanyada Rungrotmongkol, Pajaree Chariyavilaskul, Vorasuk Shotelersuk, Kearkiat Praditpornsilpa
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50211-3

Internet

https://doi.org/10.1038/s41598-023-50211-3

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