Synthesis, characterization, DFT studies and molecular docking investigation of 2-oxo-ethyl piperidine pentanamide-derived sulfonamides as anti-diabetic agents

Synthesis, characterization, DFT studies and molecular docking investigation of 2-oxo-ethyl piperidine pentanamide-derived sulfonamides as anti-diabetic agents

The present study is focused on the synthesis, characterization, DFT Studies, and in silico biological evaluation of novel benzenesulfonamides as antidiabetic agents. The compounds were synthesized and characterized experimentally using the NMR, FT-IR and HRMS while the molecular electronic structur...

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Bibliographic Details
Main Authors: Fredrick C. Asogwa, Ekoh C. Ogechi, H. Louis, Ugwu D. Izuchukwu, Chioma G. Apebende, Eze U. Florence, Martins C. Ekeleme, Ezugwu A. James, Onyinye J. Ikenyirimba, Alexander I. Ikeuba, Aniekan E. Owen, Okoro U. Chris
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Anti-diabetic
Synthesis
Sulfonamides
Piperidine
DFT
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622003915

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http://www.sciencedirect.com/science/article/pii/S2211715622003915

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