3D High‐Content Culturing and Drug Screening Platform to Study Vascularized Hepatocellular Carcinoma in Hypoxic Condition

3D High‐Content Culturing and Drug Screening Platform to Study Vascularized Hepatocellular Carcinoma in Hypoxic Condition

Hypoxia in the tumor microenvironment (TME) is the leading cause of metastasis and chemoresistance in cancer cells. Numerous 3D in vitro models have been proposed to study hypoxic stress, but none have enabled sufficient analysis of hepatocellular carcinoma (HCC). Herein, a 3D in vitro tumor vascula...

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Bibliographic Details
Main Authors: Jungeun Lim, Hyeri Choi, Jungho Ahn, Noo Li Jeon
Format: Article
Language:English
Published: Wiley-VCH 2021-12-01
Series:Advanced NanoBiomed Research
Subjects:
drug screening
hepatocellular carcinomas
hypoxia
microfluidics
vascularized tumors
Online Access:https://doi.org/10.1002/anbr.202100078

Internet

https://doi.org/10.1002/anbr.202100078

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