Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade

Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade

The bioisosteres of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles are well-known pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1,3,4-oxa-/thiadiazole nuclei have been very attractive to researchers for drug design, synthesis, and the study of their potential activity...

Full description

Bibliographic Details
Main Authors: Rana M. El-Masry, Hanan H. Kadry, Azza T. Taher, Sahar M. Abou-Seri
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
1,3,4-oxadiazole
1,3,4-thiadiazole
bioisosteres
synthesis
biological activity
structure–activity relationship
Online Access:https://www.mdpi.com/1420-3049/27/9/2709

Internet

https://www.mdpi.com/1420-3049/27/9/2709

Similar Items