Murine Tim-1 is excluded from the immunological synapse [v2; ref status: indexed, http://f1000r.es/QSgUx0]

The interaction between T cells and APCs bearing cognate antigen results in the formation of an immunological synapse (IS). During this process, many receptors and signaling proteins segregate to regions proximal to the synapse. This protein movement is thought to influence T cell function. However,...

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Bibliographic Details
Main Authors: Jean Lin, Leo Chen, Lawrence P Kane
Format: Article
Language:English
Published: F1000 Research Ltd 2012-10-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/1-10/v2