Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis

Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis

Increasing studies have revealed significant associations between TOP2A with oncogenesis and prognosis of human cancers; however, pan-cancer analysis has not been reported. Here, we explored the potential carcinogenic function and the association with clinical outcomes of TOP2A in 33 different human...

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Bibliographic Details
Main Authors: Fulai Zhao, Junli Chang, Peng Zhao, Wenyi Wang, Xingyuan Sun, Xiaoping Ma, Mengchen Yin, Yongjun Wang, Yanping Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
DNA topoisomerase II alpha
pan-cancer analysis
oncogenesis
immune cell infiltration
genetic alteration
prognostic value
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.856692/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.856692/full

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