Ebselen and Diphenyl Diselenide Inhibit SARS-CoV-2 Replication at Non-Toxic Concentrations to Human Cell Lines

Ebselen and Diphenyl Diselenide Inhibit SARS-CoV-2 Replication at Non-Toxic Concentrations to Human Cell Lines

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the causative agent of the COVID-19 pandemic, a global public health problem. Despite the numerous studies for drug repurposing, there are only two FDA-approved antiviral agents (Remdesivir and Nirmatrelvir) for non-hospitali...

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Bibliographic Details
Main Authors: Guilherme Wildner, Amanda Resende Tucci, Alessandro de Souza Prestes, Talise Muller, Alice dos Santos Rosa, Nathalia Roberto R. Borba, Vivian Neuza Ferreira, João Batista Teixeira Rocha, Milene Dias Miranda, Nilda Vargas Barbosa
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Vaccines
Subjects:
organoselenium molecules
ebselen
diphenyl diselenide
anti-SARS-CoV-2 activity
lymphocytes
antiviral
Online Access:https://www.mdpi.com/2076-393X/11/7/1222

Internet

https://www.mdpi.com/2076-393X/11/7/1222

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