TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis

Summary: Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. We found that TTF1, TrkA, and miR-204 were lowly expressed, whereas TrkB was highly expressed in undifferentiated NB tissues. Meanwhile, TTF1 expression correlated positively with TrkA and miR-204 expressi...

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Bibliographische Detailangaben
Hauptverfasser: Tianyou Yang, Jiahao Li, Zhenjian Zhuo, Huijuan Zeng, Tianbao Tan, Lei Miao, Manna Zheng, Jiliang Yang, Jing Pan, Chao Hu, Yan Zou, Jing He, Huimin Xia
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2022-07-01
Schriftenreihe:iScience
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Online Zugang:http://www.sciencedirect.com/science/article/pii/S2589004222009270