Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis

Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis

Abstract Background Inflammatory visceral pain is endogenously controlled by enkephalins locally released by mucosal CD4+ T lymphocytes in mice. The present study aimed at identifying opioid receptor(s) expressed on nociceptive sensory nerves involved in this peripheral opioid-mediated analgesia. Me...

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Bibliographic Details
Main Authors: Xavier Mas-Orea, Lilian Basso, Catherine Blanpied, Claire Gaveriaux-Ruff, Nicolas Cenac, Gilles Dietrich
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Journal of Neuroinflammation
Subjects:
Visceral pain
Opioid receptors
Nociceptors
T lymphocytes
Opioids
Intestinal inflammation
Online Access:https://doi.org/10.1186/s12974-021-02352-3

Internet

https://doi.org/10.1186/s12974-021-02352-3

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