Targeting the retinoic acid signaling pathway as a modern precision therapy against cancers

Targeting the retinoic acid signaling pathway as a modern precision therapy against cancers

Retinoic acid (RA) is a vital metabolite derived from vitamin A. RA plays a prominent role during development, which helps in embryological advancement and cellular differentiation. Mechanistically, RA binds to its definite nuclear receptors including the retinoic acid receptor and retinoid X recept...

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Bibliographic Details
Main Authors: Kousalya Lavudi, Shreya Madhav Nuguri, Zianne Olverson, Anantha Krishna Dhanabalan, Srinivas Patnaik, Rekha Rani Kokkanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
retinoic acid
aldehyde dehydrogenases
CYP26A1
cancer cell proliferation
tumor relapse
immune checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1254612/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1254612/full

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