Identification of Influenza PA<sub>N</sub> Endonuclease Inhibitors via 3D-QSAR Modeling and Docking-Based Virtual Screening
Structural and biochemical studies elucidate that PA<sub>N</sub> may contribute to the host protein shutdown observed during influenza A infection. Thus, inhibition of the endonuclease activity of viral RdRP is an attractive approach for novel antiviral therapy. In order to envisage stru...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/23/7129 |