Gaussian Accelerated Molecular Dynamics Simulations Investigation on the Mechanism of Angiotensin-Converting Enzyme (ACE) C-Domain Inhibition by Dipeptides

Angiotensin-converting enzyme (ACE)-inhibitory peptides extracted from food proteins can lower blood pressure by inhibiting ACE activity. A recent study showed that the inhibitory activity of IY (Ile-Tyr, a dipeptide derived from soybean protein) against ACE was much higher than that of LL (Leu-Leu)...

Full description

Bibliographic Details
Main Authors: Congcong Li, Kaifeng Liu, Siao Chen, Lu Han, Weiwei Han
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/11/3/327