Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy

Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy

Abstract Background Epilepsy affects ∼60 million people worldwide. Most antiseizure medications in the market act on voltage-gated sodium or calcium channels, indirectly modulating neurotransmitter GABA or glutamate levels or multiple targets. Earlier studies made significant efforts to directly del...

Full description

Bibliographic Details
Main Authors: Abhijna Ballal R, Shivakumar Reddy K, Divya Chandran, Sumukha Hegde, Raghavendra Upadhya, Praveen Kumar SE, Smita Shenoy, Vasudha Devi, Dinesh Upadhya
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Stem Cell Research & Therapy
Subjects:
Extracellular vesicles
Pluripotent stem cells
Neurotransmitter GABA
Epilepsy
Intranasal administration
Online Access:https://doi.org/10.1186/s13287-024-03721-4

Internet

https://doi.org/10.1186/s13287-024-03721-4

Similar Items