Ginsenoside Rc attenuates DSS-induced ulcerative colitis, intestinal inflammatory, and barrier function by activating the farnesoid X receptor

Objectives: Farnesoid X receptor (FXR) activation is involved in ameliorating inflammatory bowel disease (IBD), such as ulcerative colitis (UC), and inflammatory regulation may be involved in its mechanism. Ginsenoside Rc (Rc) is a major component of Panax ginseng, and it plays an excellent role in...

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Main Authors: Kaijia Tang, Danli Kong, Yuan Peng, Jingyi Guo, Yadi Zhong, Haibing Yu, Zhenhua Mai, Yanling Chen, Yingjian Chen, Tianqi Cui, Siwei Duan, Tianyao Li, Naihua Liu, Dong Zhang, Yuanlin Ding, Jiawen Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1000444/full